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The Phantom Fever

30
4.7

Course Overview
This accredited continuing nursing education activity explores the clinical complexities of diagnosing central line-associated bloodstream infections (CLABSIs) in the presence of negative cultures and nonspecific systemic signs. Through a compelling case narrative, learners will follow the journey of a patient whose persistent fever and subtle hemodynamic changes defied traditional sepsis workups. The episode emphasizes the role of vigilant nursing observation, critical pattern recognition, and interdisciplinary collaboration in uncovering occult fungal colonization as the source of persistent febrile episodes. Learners will deepen their understanding of CLABSI pathophysiology, fungal line infections, and the importance of challenging premature diagnostic closure in critically ill patients. 

Listen, Learn, and Earn CE Hours with this podcast course. Available on Apple, Spotify, and other podcast apps. 

Learning Outcomes 
Upon the completion of this course, the learner should be able to:

  • Recognize the potential for fungal colonization of central lines to produce systemic symptoms without positive blood cultures.
  • Explain the pathophysiology of CLABSI, including the role of Candida species in biofilm formation and intermittent symptomatology.
  • Apply clinical reasoning to assess persistent fever in ICU patients despite negative cultures and normal imaging.
  • Evaluate central line integrity and usage patterns to determine if the line may be a source of infection.
  • Advocate for timely central line removal and catheter tip culture when other sources of fever have been ruled out.

About the Author/Presenter 
Mike Linares MSN, RN has over 15 years of experience in healthcare, including work as a Registered Nurse, EMT and paramedic. After a challenging nursing school experience he was motivated to create and found SimpleNursing, a platform dedicated to providing accessible and effective study resources for nursing students. Having helped over 1 million students become nurses, he continues to focus his efforts on educating and inspiring the next generation of nurses.

Audience/Accreditations and Approvals 
TRC Healthcare/ NetCE 
In support of improving patient care, this activity has been planned and implemented by TRC Healthcare/ NetCE. TRC Healthcare/NetCE is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. 
This course is designed for the following healthcare professions (select your profession for details): 
Nursing

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