Oral Cancer and Complications of Cancer Therapies

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Course Overview
Millions of people are diagnosed with a variety of malignant neoplastic lesions each year. Oral cancer, in which the primary malignancy arises within the oral cavity, is the 8th most common cancer in men and the 14th most common cancer in women. The common element among this diverse patient group are the problems encountered post-surgically when chemotherapy and or radiotherapy are used to destroy malignant cells, which can remain after the completion of surgery. Malignant lesions in the oral cavity are usually treated by surgical removal and several weeks of radiotherapy. The latter modality can cause severe changes in the mucosal tissues, bone, salivary glands, and the teeth, most of which are irreversible. Proper management before, during, and after both modes of therapy will have a positive impact on the quality of life and decrease the morbidity associated with these treatment regimens. This course will discuss the changes experienced within the oral environment during and after the treatment for oral and systemic cancers. Methods to mitigate these problems and to decrease the morbidity and the mortality which afflict these patients will be reviewed.

Learning Outcomes 
Upon the completion of this course, the learner should be able to:

  • Identify the most common etiologies of oral cancer and its incidence within the population.
  • Review the basic histology of the oral mucosa and the changes that occur with premalignant and malignant lesions and their patterns of occurrence.
  • Compare and contrast erythroplakic lesions and leukoplakic lesions.
  • Distinguish among the varied diagnostic procedures for suspicious oral lesions and the classification and staging of those that are found to be malignant.
  • Review the principles of and the complications from radiotherapy utilized postsurgically for patients with oral cancer.
  • List dental procedures that should be completed before surgery and radiotherapy that can minimize oral complications after the completion of these treatment modalities.
  • Explain the basic principles by which chemo­therapeutic agents exert their cytotoxic effect.
  • Discuss the serious chemotherapy-induced infections of oral origin that can be disseminated systemically.
  • List other common oral effects of chemotherapy.

About the Author/Presenter 
Mark J. Szarejko, DDS, FAGD, received his dental degree from the State University of New York at Buffalo in 1985. He received fellowship from the Academy of General Dentistry in 1994.

Audience/Accreditations and Approvals 
TRC Healthcare/ NetCE 
In support of improving patient care, this activity has been planned and implemented by TRC Healthcare/ NetCE. TRC Healthcare/NetCE is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. 
This course is designed for the following healthcare professions (select your profession for details): 
Dental AGD Code: 730, Nursing, Physician

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