A Nurse’s Primer on Parkinson’s Disease

Providing effective care for patients with Parkinson’s disease can feel challenging. The neurodegenerative disorder affects approximately 1% of individuals older than 60 years of age, and its complex symptoms require a comprehensive approach. As a nurse, you’re on the front lines of patient care, making your knowledge and observation skills vital to managing this disease. 

Parkinson’s disease results from the loss of dopamine-producing cells in the brain and the deposition of Lewy bodies. Because there is no definitive test for the condition, healthcare teams rely heavily on clinical findings and the pattern of symptom progression. Your ability to assess changes in a patient’s physical and mental state directly impacts their quality of life. 

By understanding the key motor and non-motor symptoms, you can better support your patients through their journey. Providing excellent nursing care for Parkinson’s involves managing medications, offering emotional support, and collaborating with an interprofessional team. 

Related CE course for nurses: Parkinson’s Disease 

Recognizing primary motor and non-motor symptoms 

Patients with idiopathic Parkinson’s typically exhibit an asymmetrical presentation of motor symptoms. You will often observe bradykinesia, which is a noticeable slowness of movement. Other primary motor symptoms include resting tremors, muscle rigidity, and postural or gait instability. 

While motor symptoms are highly visible, non-motor symptoms frequently cluster into broader categories of abnormality. These include neuropsychiatric disorders, autonomic dysfunction, sleep disorders, and pain. Conditions like sleep behavior disorder, constipation, and depression can manifest before, during, or after the onset of motor symptoms. Because diagnosis rests on a history and physical examination, your careful questioning of patients and family members regarding the sequence of these symptoms is critical. 

Key strategies in nursing care for Parkinson’s 

Effective long-term management requires a coordinated, interprofessional team approach. A major component of nursing care for Parkinson’s involves vigilant medication management. Treatments aim to replace or mimic dopamine, but they come with significant side effects that require your constant monitoring. 

When patients take levodopa, monitor them for changes in blood pressure, pulse, and mental status. Be aware that with prolonged therapy and disease progression, the duration of benefit from each dose often becomes shorter. For patients on dopamine agonists like pramipexole or ropinirole, watch for daytime alertness, weight changes, hallucinations, impulse control disorders, and orthostatic hypotension. 

Other medications require specific observations. If a patient uses a rotigotine patch, monitor for skin reactions and ensure you remove the patch prior to an MRI. For those on tolcapone, regularly test liver enzymes and function. Always check for drug interactions and changes in cardiac or mental status when administering monoamine oxidase inhibitors like selegiline and rasagiline. 

Overcoming medication non-adherence 

Adhering to a strict medication schedule is difficult for many patients. When addressing medication non-adherence, use nonjudgmental interviewing skills. Encourage your patients to admit missed doses without fear of disapproval or termination of care. 

Take the time to explore their barriers to adherence. Apply clinical resources to help surmount these challenges, offering simple explanations of how medications work optimally when taken correctly. If necessary, refer your patients to non-adherence counseling to ensure they get the support they need. 

Providing psychological and emotional support 

Neuropsychiatric conditions are incredibly common in Parkinson’s disease. You can help identify these comorbidities early by utilizing standardized screening tests. The American Academy of Neurology recommends tools like the Beck Depression Inventory or Geriatric Depression Scale for depression, and the Mini-Mental State Examination or Montreal Cognitive Assessment for dementia. 

Managing psychosis and hallucinations 

Up to 60% of patients with Parkinson’s develop psychosis, which often becomes a persistent, lifelong problem. Early clinical manifestations typically include visual hallucinations, with patients initially remaining lucid. Risk factors for psychosis include cognitive impairment, advanced age, sleep disturbances, and disease severity. 

Treating psychosis requires a delicate balance. Dopaminergic agents used for motor control can worsen psychotic symptoms, while antipsychotic agents can exacerbate motor symptoms. You should help control triggering factors like infections, metabolic disorders, and sleep disruptions. 

When reviewing medications, look to reduce polypharmacy, tricyclic antidepressants, and sedatives. First-generation antipsychotics like haloperidol and certain atypical antipsychotics like olanzapine should not be used, as they worsen parkinsonism. Low-dose clozapine is often a first-line choice, though it requires mandatory routine blood neutrophil counts due to the risk of agranulocytosis. 

Navigating dementia and depression 

Dementia management involves the careful discontinuation of potential aggravators. Work with the prescribing provider to halt anticholinergics, amantadine, tricyclic antidepressants, and benzodiazepines. Providers will typically initiate a cholinesterase inhibitor like rivastigmine or donepezil to help manage cognitive decline. 

Depression is another significant hurdle. Symptoms confined to “off” times may respond well to treatments that reduce motor fluctuations. Otherwise, tricyclic antidepressants are often considered the best choice for treating depression in this population, followed by selective serotonin reuptake inhibitors. 

Empower your nursing career with continuing education 

Providing excellent nursing care for Parkinson’s requires patience, observation, and a commitment to ongoing learning. By mastering medication management and understanding the nuances of non-motor symptoms like psychosis and depression, you can dramatically improve the lives of your patients.